Regulatory T Cells Resist Cyclosporine-Induced Cell Death via CD44-Mediated Signaling Pathways

Cyclosporine A (CSA) is an immunosuppressive agent that specifically targets T cells and also increases the percentage of pro-tolerogenic CD4+Foxp3+ regulatory T cells (Treg) through unknown mechanisms. We previously reported that CD44, a receptor for the extracellular matrix glycosaminoglycan hyalu...

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Bibliographic Details
Main Authors: Shannon M. Ruppert, Ben A. Falk, S. Alice Long, Paul L. Bollyky
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2015/614297
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