Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity
Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is one of the dietary flavonoids, distributed in medicinal plants, vegetables, and fruits. Quercetin has the ability to bind with several metal ions to increase its biological activities. In the last two decades, quercetin has attracted considerable attent...
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Language: | English |
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Wiley
2021-01-01
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Series: | Bioinorganic Chemistry and Applications |
Online Access: | http://dx.doi.org/10.1155/2021/8818452 |
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author | Zahra Moodi Ghodsieh Bagherzade Janny Peters |
author_facet | Zahra Moodi Ghodsieh Bagherzade Janny Peters |
author_sort | Zahra Moodi |
collection | DOAJ |
description | Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is one of the dietary flavonoids, distributed in medicinal plants, vegetables, and fruits. Quercetin has the ability to bind with several metal ions to increase its biological activities. In the last two decades, quercetin has attracted considerable attention due to the biological and pharmaceutical activities such as antioxidant, antibacterial, and anticancer. In the present study, quercetin and ethanolamine were used for the synthesis Schiff base complex, which was characterized by IR, 1H NMR, and 13C NMR spectroscopy. The Schiff base has been employed as a ligand for the synthesis of novel nanoscale Cu (II) complex. The product was characterized by FT-IR spectroscopy, FESEM, and XRD. Significantly, the product showed remarkable catalytic activity towards the oxidation of primary and secondary alcohols. The antibacterial activity of the final product was assessed against Staphylococcus aureus (Gram‐positive) and Escherichia coli (Gram‐negative) bacteria using an inhibition zone test. The synthesized nanoscale Cu (II) complex exhibited a strong antibacterial activity against both Gram-positive and Gram-negative bacteria. |
format | Article |
id | doaj-art-0fb5ea0584dc4443bd6558fdb7bd9f20 |
institution | Kabale University |
issn | 1565-3633 1687-479X |
language | English |
publishDate | 2021-01-01 |
publisher | Wiley |
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series | Bioinorganic Chemistry and Applications |
spelling | doaj-art-0fb5ea0584dc4443bd6558fdb7bd9f202025-02-03T01:25:45ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2021-01-01202110.1155/2021/88184528818452Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial ActivityZahra Moodi0Ghodsieh Bagherzade1Janny Peters2Department of Chemistry, University of Birjand, Birjand 97175-615, IranDepartment of Chemistry, University of Birjand, Birjand 97175-615, IranDepartment of Plant Systems Physiology, Radboud University Nijmegen, Nijmegen 6525, AJ, NetherlandsQuercetin (3,3′,4′,5,7-pentahydroxyflavone) is one of the dietary flavonoids, distributed in medicinal plants, vegetables, and fruits. Quercetin has the ability to bind with several metal ions to increase its biological activities. In the last two decades, quercetin has attracted considerable attention due to the biological and pharmaceutical activities such as antioxidant, antibacterial, and anticancer. In the present study, quercetin and ethanolamine were used for the synthesis Schiff base complex, which was characterized by IR, 1H NMR, and 13C NMR spectroscopy. The Schiff base has been employed as a ligand for the synthesis of novel nanoscale Cu (II) complex. The product was characterized by FT-IR spectroscopy, FESEM, and XRD. Significantly, the product showed remarkable catalytic activity towards the oxidation of primary and secondary alcohols. The antibacterial activity of the final product was assessed against Staphylococcus aureus (Gram‐positive) and Escherichia coli (Gram‐negative) bacteria using an inhibition zone test. The synthesized nanoscale Cu (II) complex exhibited a strong antibacterial activity against both Gram-positive and Gram-negative bacteria.http://dx.doi.org/10.1155/2021/8818452 |
spellingShingle | Zahra Moodi Ghodsieh Bagherzade Janny Peters Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity Bioinorganic Chemistry and Applications |
title | Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity |
title_full | Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity |
title_fullStr | Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity |
title_full_unstemmed | Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity |
title_short | Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity |
title_sort | quercetin as a precursor for the synthesis of novel nanoscale cu ii complex as a catalyst for alcohol oxidation with high antibacterial activity |
url | http://dx.doi.org/10.1155/2021/8818452 |
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