Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Abstract In situ radiotherapy is the most successful cytotoxic therapy available for the treatment of solid tumors, while high‐dose radiotherapy per fraction is not yet widely and reliably used. To some extent, the major considerations of the disappointing results are on the risk of high‐dose irradi...

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Main Authors: Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
hypofractionated radiotherapy
immunomodulatory effect
nanovaccination
radiosensitization
tumor‐targeting nanoparticles
verteporfin
Online Access:https://doi.org/10.1002/advs.202413387
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https://doi.org/10.1002/advs.202413387

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