Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis
Purpose. To report the onset of severe macular edema in adolescent female patients affected by juvenile idiopathic arthritis (JIA). Methods. Four female patients affected by JIA-related chronic anterior uveitis (CAU), complicated by severe macular edema, were retrospectively analyzed. Macular area w...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/803989 |
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| author | Maria Pia Paroli Claudia Fabiani Giovanni Spinucci Irene Abicca Alfredo Sapia Leopoldo Spadea |
| author_facet | Maria Pia Paroli Claudia Fabiani Giovanni Spinucci Irene Abicca Alfredo Sapia Leopoldo Spadea |
| author_sort | Maria Pia Paroli |
| collection | DOAJ |
| description | Purpose. To report the onset of severe macular edema in adolescent female patients affected by juvenile idiopathic arthritis (JIA). Methods. Four female patients affected by JIA-related chronic anterior uveitis (CAU),
complicated by severe macular edema, were retrospectively analyzed. Macular area was evaluated by fluorescein angiography and optical coherence tomography (OCT). Results. CAU was bilateral in three patients. Mean age of uveitis and arthritis onset was, respectively,
4.5±1.7 years and 6.0±3.9 years. All patients underwent cataract extraction surgery. Despite ocular inflammation being controlled by topical/systemic therapy, during adolescence (mean age of appearance/diagnosis:
12.7±3.9 years) patients developed severe
unilateral macular edema. OCT revealed massive macular thickening (range from 550 μm to 1214 μm). Conclusions. Macular edema appeared in female adolescent patients in eyes with long-dating CAU submitted to cataract surgery. In such patients, in presence of age-related microvascular changes due to the enhancer effect of sex hormones, cataract extraction should be a factor triggering the retinal complication. |
| format | Article |
| id | doaj-art-0f34968526c846eabc8e7e028099b1fc |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-0f34968526c846eabc8e7e028099b1fc2025-02-03T06:07:17ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302013-01-01201310.1155/2013/803989803989Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related UveitisMaria Pia Paroli0Claudia Fabiani1Giovanni Spinucci2Irene Abicca3Alfredo Sapia4Leopoldo Spadea5Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyDepartment of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyDepartment of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyDepartment of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyDepartment of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, ItalyDepartment of Biotechnological and Applied Clinical Sciences, Eye Clinic, University of L’Aquila, ItalyPurpose. To report the onset of severe macular edema in adolescent female patients affected by juvenile idiopathic arthritis (JIA). Methods. Four female patients affected by JIA-related chronic anterior uveitis (CAU), complicated by severe macular edema, were retrospectively analyzed. Macular area was evaluated by fluorescein angiography and optical coherence tomography (OCT). Results. CAU was bilateral in three patients. Mean age of uveitis and arthritis onset was, respectively, 4.5±1.7 years and 6.0±3.9 years. All patients underwent cataract extraction surgery. Despite ocular inflammation being controlled by topical/systemic therapy, during adolescence (mean age of appearance/diagnosis: 12.7±3.9 years) patients developed severe unilateral macular edema. OCT revealed massive macular thickening (range from 550 μm to 1214 μm). Conclusions. Macular edema appeared in female adolescent patients in eyes with long-dating CAU submitted to cataract surgery. In such patients, in presence of age-related microvascular changes due to the enhancer effect of sex hormones, cataract extraction should be a factor triggering the retinal complication.http://dx.doi.org/10.1155/2013/803989 |
| spellingShingle | Maria Pia Paroli Claudia Fabiani Giovanni Spinucci Irene Abicca Alfredo Sapia Leopoldo Spadea Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis Case Reports in Ophthalmological Medicine |
| title | Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis |
| title_full | Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis |
| title_fullStr | Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis |
| title_full_unstemmed | Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis |
| title_short | Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis |
| title_sort | severe macular edema in patients with juvenile idiopathic arthritis related uveitis |
| url | http://dx.doi.org/10.1155/2013/803989 |
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