Clinico-genomic study reveals association of dengue virus genome high frequency mutations with dengue disease severity

Clinico-genomic study reveals association of dengue virus genome high frequency mutations with dengue disease severity

Abstract Transmission of the dengue virus (DENV) places a huge burden on public health in several endemic regions. Like other RNA viruses, mutations in the DENV genome greatly governs its virulence, transmissibility, and interaction with the host immune system. Present study focuses on integrated an...

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Main Authors: Varsha Ravi, Md Imran, Kriti Khare, Pallavi Mishra, Ramakant Mohite, Kanika, Md Abuzar Khan, Aparna Swaminathan, Aanchal Yadav, Sristi Sinha, Richa Shukla, Partha Chattopadhyay, Jyoti Soni, Ranjeet Maurya, Tavpritesh Sethi, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Mutation analysis
Disease severity
Dengue
Leukopenia
Thrombocytopenia
Online Access:https://doi.org/10.1038/s41598-025-00462-z
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https://doi.org/10.1038/s41598-025-00462-z

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