Integrated network pharmacology reveals the mechanism of action of Xianlinggubao prescription for inflammation in osteoarthritis
Abstract Background Osteoarthritis (OA), a leading cause of disability worldwide, is characterized by complex interactions between cartilage degradation and synovial inflammation. While NSAIDs are the primary treatment, their prolonged use exacerbates gastrointestinal risks and does not alter diseas...
Saved in:
| Main Authors: | Jingyi Hou, Yubo Li, Yu Zhang, Ning Yang, Bin Chen, Guiyun Ma, Naiqiang Zhu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | BMC Complementary Medicine and Therapies |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12906-025-04928-5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CIP2A promotes inflammation and exacerbates osteoarthritis by targeting CEMIP
by: Jingyue Su, et al.
Published: (2025-06-01) -
Platelet-rich plasma relieves inflammation and pain by regulating M1/M2 macrophage polarization in knee osteoarthritis rats
by: Jiawei Xu, et al.
Published: (2025-04-01) -
Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization
by: Qi Sun, et al.
Published: (2025-01-01) -
Integrated bioinformatics and network pharmacology to identify and validate macrophage polarization related hub genes in the treatment of osteoarthritis with Astragalus membranaceus
by: Hui Zang, et al.
Published: (2025-05-01) -
A bibliometric analysis of studies related to the nuclear factor kappa B signaling pathway in knee osteoarthritis between 2004 and 2023
by: Yafeng Mo, et al.
Published: (2025-06-01)