Ga@MXene-based flexible wearable biosensor for glucose monitoring in sweat

Summary: Most wearable biosensors struggle to balance flexibility and conductivity in their sensing interfaces. In this study, we propose a wearable sensor featuring a highly stretchable, three-dimensional conductive network structure based on liquid metal. The sensor interface utilizes a patterned...

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Bibliographic Details
Main Authors: Wensi Zhang, Shuyue Jiang, Hongquan Yu, Shilun Feng, Kaihuan Zhang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S258900422402964X
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Summary:Summary: Most wearable biosensors struggle to balance flexibility and conductivity in their sensing interfaces. In this study, we propose a wearable sensor featuring a highly stretchable, three-dimensional conductive network structure based on liquid metal. The sensor interface utilizes a patterned Ga@MXene hydrogel system, where gallium (Ga) grafted onto MXene provides enhanced electrical conductivity and malleability. MXene provides excellent conductivity and a three-dimensional layered structure. Additionally, the chitosan (CS) hydrogel, with its superior water absorption and stretchability, allows the electrode to retain sweat and closely stick to the skin. The sensor demonstrates a low limit of detection (0.77 μM), high sensitivity (1.122 μA⋅μM⁻1⋅cm⁻2), and a broad detection range (10–1,000 μM), meeting the requirements for a wide range of applications. Notably, the sensor can also induce perspiration in the wearer. The three-dimensional porous structure of the Ga@MXene/CS biosensor ensures excellent conductivity and flexibility, making it suitable for a variety of applications.
ISSN:2589-0042