The dual role of autophagy in cancer stem cells: implications for tumor progression and therapy resistance

Abstract Cancer stem cells (CSCs) constitute a small yet crucial subgroup in tumors, known for their capacity to self-renew, differentiate, and promote tumor growth, metastasis, and resistance to therapy. These characteristics position CSCs as significant factors in tumor recurrence and unfavorable...

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Bibliographic Details
Main Authors: Haiqing Jia, Jing Wei, Wei Zheng, Zhuo Li
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06595-z
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