Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys

Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys

Efgartigimod is a human IgG1 antibody Fc fragment that reduces IgG levels through neonatal Fc receptor blockade. This study evaluated whether efgartigimod affects the generation of T-cell-dependent antibodies and cellular immune responses to keyhole limpet hemocyanin (KLH) immunization in non-human...

Full description

Saved in:
Bibliographic Details
Main Authors: Ornella Binazon, Mario Cocco, Daniel Thwaites, Christopher Cooper, Mahan Moshir, Peter Vanhoenacker, Dieter Defever, Ariëlla Van de Sompel, Sophie Steeland, Gwenda Pynaert, Peter Ulrichts, Judith Baumeister
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Immunotoxicology
Subjects:
Efgartigimod
neonatal Fc receptor
immunoglobulin G
keyhole limpet hemocyanin
immune response
antibody
Online Access:https://www.tandfonline.com/doi/10.1080/1547691X.2025.2459934
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.tandfonline.com/doi/10.1080/1547691X.2025.2459934

Similar Items