Heterostilbene Carbamates with Selective and Remarkable Butyrylcholinesterase Inhibition: Computational Study and Physico-Chemical Properties

Heterostilbene Carbamates with Selective and Remarkable Butyrylcholinesterase Inhibition: Computational Study and Physico-Chemical Properties

This manuscript reports the synthesis and characterization of 19 novel heterostilbene carbamates, designed as selective butyrylcholinesterase (BChE) inhibitors with potential applications in the treatment of neurodegenerative disorders, particularly Alzheimer’s disease. The compounds were synthesize...

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Bibliographic Details
Main Authors: Anamarija Raspudić, Ilijana Odak, Milena Mlakić, Antonija Jelčić, Karla Bulava, Karla Karadža, Valentina Milašinović, Ivana Šagud, Paula Pongrac, Dora Štefok, Danijela Barić, Irena Škorić
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
anti-inflammatory activity
butyrylcholinesterase inhibition
carbamates
docking
molecular dynamics
synthesis
Online Access:https://www.mdpi.com/2218-273X/15/6/825
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