Enhanced FOXO1 expression as a predictor of decitabine response and prolonged survival in high-risk myelodysplastic syndrome

Enhanced FOXO1 expression as a predictor of decitabine response and prolonged survival in high-risk myelodysplastic syndrome

Purpose The aim of this study was to assess the predictive role of FOXO1 expression changes in determining the response to hypomethylation therapy in patients with high-risk myelodysplastic syndrome (MDS).Methods FOXO1 mRNA levels were measured using real-time PCR in 62 newly diagnosed MDS patients...

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Bibliographic Details
Main Authors: Hong Liu, Zheng Zhang, Nanfang Huang, Feng Xu, Sida Zhao, Chunkang Chang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Hematology
Subjects:
Myelodysplastic syndromes
decitabine
treatment response
immunity
polarization
prognosis
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2025.2506862
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https://www.tandfonline.com/doi/10.1080/16078454.2025.2506862

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