Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies

HIV-1’s subtype C V3 loop consensus sequence exhibits increased resistance to anti-V3 antibody-mediated neutralization as compared to the subtype B consensus sequence. The dynamic 3D structure of the consensus C V3 loop crown, visualized by ab initio folding, suggested that the resistance derives fr...

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Bibliographic Details
Main Authors: David Almond, Chavdar Krachmarov, James Swetnam, Susan Zolla-Pazner, Timothy Cardozo
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2012/803535
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