Statins Activate Human PPAR𝛼 Promoter and Increase PPAR𝛼 mRNA Expression and Activation in HepG2 Cells
Statins increase peroxisome proliferator-activated receptor 𝛼 (PPAR𝛼) mRNA expression, but the mechanism of this increased PPAR𝛼 production remains elusive. To examine the regulation of PPAR𝛼 production, we examined the effect of 7 statins (atorvastatin, cerivastatin, fluvastatin, pitavastatin, prav...
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Main Authors: | Makoto Seo, Ikuo Inoue, Masaaki Ikeda, Takanari Nakano, Seiichiro Takahashi, Shigehiro Katayama, Tsugikazu Komoda |
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Format: | Article |
Language: | English |
Published: |
Wiley
2008-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2008/316306 |
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