Synthesis, Computational Studies and Preliminary Pharmacological Evaluation of New Arylpiperazines
A series of novel arylpiperazines were synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced climbing behavior (D2 antagonism), 5-HTP induced head twitches (5-HT2A antagonism) and catalepsy studies in albino mice. The physicochemical similarity of...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2011/346087 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|