Regulation of TXB2 and PGE2 production by TGF-β1 in in vitro silica dust-exposed rat alveolar macrophage

We investigated the effect of transforming factor factor-β1 (TGF-β1) on thromboxane B2 (TXB2) and prostaglandin E2 (PGE2) production in in vitro silica dust-exposed rat alveolar macrophages (AM). In the presence of 5 μg of anti-TGF-β1 antibodies, TXB2 production decreased, but PGE2 production increa...

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Bibliographic Details
Main Authors: Urszula Orlinska, Douglas C. Kuhn
Format: Article
Language:English
Published: Wiley 1995-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935195000664
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