Total and Structural Carotid Artery Stiffness Are Associated With Cognitive Decline and Structural Brain Abnormalities Related to Alzheimer Disease and Alzheimer Disease‐Related Dementias Pathology: The Multi‐Ethnic Study of Atherosclerosis

Total and Structural Carotid Artery Stiffness Are Associated With Cognitive Decline and Structural Brain Abnormalities Related to Alzheimer Disease and Alzheimer Disease‐Related Dementias Pathology: The Multi‐Ethnic Study of Atherosclerosis

Background Arterial stiffness is associated with pathological changes underlying Alzheimer disease and related dementias. Total pulse wave velocity can be subdivided into 2 main mechanisms: structural arterial stiffness (S‐PWV) due to intrinsic remodeling of the artery wall and load‐dependent arteri...

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Main Authors: Jeremy R. Williams, Theodore M. DeConne, Ryan Pewowaruk, Claudia Korcarz, Jordan Tanley, Cynthia Carlsson, Susan R. Heckbert, Mohamad Habes, Ilya Nasrallah, Samuel N. Lockhart, José A. Luchsinger, Jingzhong Ding, Kathleen M. Hayden, Timothy M. Hughes, Adam D. Gepner
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
arterial stiffness
cognition
MESA
MRI brain abnormalities
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.039925
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https://www.ahajournals.org/doi/10.1161/JAHA.124.039925

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