Relation between Genomic DNA Breakpoints in MLL Gene and Treatment Outcome in Infants with Acute Leukemia

Relation between Genomic DNA Breakpoints in MLL Gene and Treatment Outcome in Infants with Acute Leukemia

Aim. To evaluate the relation between genomic DNA breakpoints in MLL and translocation partner genes (TPG) and clinical parameters of infant AL. Methods. 68 infants (29 boys and 39 girls with median age of 4.8 mo) with MLL-rearranged acute lymphoblastic leukemia (ALL) (n = 46), acute myeloid leuk...

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Main Authors: GA Tsaur, C Meyer, TO Riger, AM Kustanovich, EV Fleischman, YuV Ol’shanskaya, AM Popov, OI Sokova, EA Matveeva, OV Nikulina, AE Drui, OR Arakaev, OV Streneva, SA Rumyantsev, EV Shorikov, AG Solodovnikov, LI Savel’ev, R Marschalek, LG Fechina
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2016-01-01
Series:Клиническая онкогематология
Subjects:
acute leukemia
infants
11q23/MLL rearrangements
MLL-Baby
treatment outcome
Online Access:http://bloodjournal.ru/en/relation-between-genomic-dna-breakpoints-in-mll-gene-and-treatment-outcome-in-infants-with-acute-leukemia/
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http://bloodjournal.ru/en/relation-between-genomic-dna-breakpoints-in-mll-gene-and-treatment-outcome-in-infants-with-acute-leukemia/

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