Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential

Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential

Abstract We introduce a family of membrane-targeted azobenzenes (MTs) with a push-pull character as a new tool for cell stimulation. These molecules are water soluble and spontaneously partition in the cell membrane. Upon light irradiation, they isomerize from trans to cis, changing the local charge...

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Main Authors: Valentina Sesti, Arianna Magni, Matteo Moschetta, Chiara Florindi, Marlene E. Pfeffer, Mattia Lorenzo DiFrancesco, Michele Guizzardi, Giulia Folpini, Luca Sala, Alessandra Gilda Ritacca, Beatrice Campanelli, Paola Moretti, Giuseppe Maria Paternò, Luca Maragliano, Matteo Tommasini, Francesco Lodola, Elisabetta Colombo, Fabio Benfenati, Chiara Bertarelli, Guglielmo Lanzani
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-024-01669-x
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https://doi.org/10.1038/s41377-024-01669-x

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