PRMT5 Maintains Homeostasis of the Intestinal Epithelium by Modulating Cell Proliferation and Survival

PRMT5 Maintains Homeostasis of the Intestinal Epithelium by Modulating Cell Proliferation and Survival

Abstract Intestinal homeostasis is sustained by self‐renewal of intestinal stem cells, which continuously divide and produce proliferative transit‐amplifying (TA) and progenitor cells. Protein arginine methyltransferases 5 (PRMT5) plays a crucial role in regulating homeostasis of various mammalian t...

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Bibliographic Details
Main Authors: Leilei Li, Zhe Zhang, Xu Wang, Haiyong Zhao, Liansheng Liu, Yanhui Xiao, Shan Hua, Ye‐Guang Chen
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Advanced Science
Subjects:
cell proliferation and survival
intestinal homeostasis
protein arginine methylation
protein arginine methyltransferases 5
stem cells
Online Access:https://doi.org/10.1002/advs.202415559
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