Transcriptome analysis reveals the anticancer effects of fenbendazole on ovarian cancer: an in vitro and in vivo study

Transcriptome analysis reveals the anticancer effects of fenbendazole on ovarian cancer: an in vitro and in vivo study

Abstract New treatment strategies for ovarian cancer, which is the deadliest female reproductive tract malignancy, are urgently needed. Here, we investigated the anticancer effects of fenbendazole (FBZ), a benzimidazole compound, on the regulation of apoptosis and mitotic catastrophe in A2780 and SK...

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Bibliographic Details
Main Authors: Xin Wang, Wenda Tian, Ning Wang, Xiangqun Yang, Zhenyan Liu, Lvzhou Li, Taoyu Zhao, Chuanlin Wang, Hongping Zhang, Hongying Yang, Yue Jia
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Cancer
Subjects:
Fenbendazole
Ovarian cancer
Apoptosis
Mitotic catastrophe
Online Access:https://doi.org/10.1186/s12885-024-13361-9
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https://doi.org/10.1186/s12885-024-13361-9

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