The two major splice variants of scavenger receptor BI differ by their interactions with lipoproteins and cellular localization in endothelial cells

The two major splice variants of scavenger receptor BI differ by their interactions with lipoproteins and cellular localization in endothelial cells

The scavenger receptor BI (SR-BI) facilitates the transport of both HDL and LDL through endothelial cells. Its two splice variants, SR-BIvar1 and SR-BIvar2, differ in their carboxy terminal domains. Only SR-BIvar1 contains the putative binding sites for the adapter proteins PDZ domain containing pro...

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Bibliographic Details
Main Authors: Anton Potapenko, Kathrin Frey, Eveline Schlumpf, Jérôme Robert, Bernd Wollscheid, Arnold von Eckardstein, Lucia Rohrer
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Lipid Research
Subjects:
endothelial cells
lipoproteins
SR-BI
PDZK1
DOCK4
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524001706
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