(-)-Fenchone Ameliorates TNBS-Induced Colitis in Rats via Antioxidant, Immunomodulatory, and Cytoprotective Mechanisms

(-)-Fenchone Ameliorates TNBS-Induced Colitis in Rats via Antioxidant, Immunomodulatory, and Cytoprotective Mechanisms

Background: (-)-Fenchone is a bicyclic monoterpene present in the plant species <i>Foeniculum vulgare</i> Mill, <i>Thuja occidentalis</i> L. (tuja), and <i>Lavandula stoechas</i> (lavender). These plants have therapeutic value in the treatment of intestinal disord...

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Main Authors: Maria Elaine Cristina Araruna, Edvaldo Balbino Alves Júnior, Catarina Alves de Lima Serafim, Matheus Marley Bezerra Pessoa, Michelle Liz de Souza Pessôa, Vitória Pereira Alves, Marianna Vieira Sobral, Marcelo Sobral da Silva, Adriano Francisco Alves, Maria Carolina de Paiva Sousa, Aurigena Antunes Araújo, Leônia Maria Batista
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
(-)-fenchone
ulcerative colitis
antioxidant
immunomodulatory
cytoprotection
Online Access:https://www.mdpi.com/1424-8247/18/1/18
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