The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma
Hibernoma is a rare benign lipogenic tumor of brown fat that develops in a wide variety of locations. Although the features of hibernoma demonstrated by MRI resemble those of liposarcoma, recent FDG-PET/CT studies have documented higher radiotracer uptake than liposarcoma, suggesting that FDG/PET/CT...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Orthopedics |
| Online Access: | http://dx.doi.org/10.1155/2015/958690 |
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| _version_ | 1832565074183585792 |
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| author | Jong Hoon Park Koichi Ogura Tomohiro Fujiwara Akihito Nagano Kunihiko Numoto Takashi Terauchi Akihiko Yoshida Akira Kawai |
| author_facet | Jong Hoon Park Koichi Ogura Tomohiro Fujiwara Akihito Nagano Kunihiko Numoto Takashi Terauchi Akihiko Yoshida Akira Kawai |
| author_sort | Jong Hoon Park |
| collection | DOAJ |
| description | Hibernoma is a rare benign lipogenic tumor of brown fat that develops in a wide variety of locations. Although the features of hibernoma demonstrated by MRI resemble those of liposarcoma, recent FDG-PET/CT studies have documented higher radiotracer uptake than liposarcoma, suggesting that FDG/PET/CT is useful for differentiating hibernoma from liposarcoma. Here we report two cases of hibernoma that showed relatively lower SUVs than those reported previously, lying within the range for liposarcoma. Our findings emphasize that hibernoma needs to be included in the differential diagnosis of any fat-containing tumor showing intense accumulation by FDG-PET/CT. Although it is unlikely that such a rare condition could be reasonably diagnosed on the basis of MRI and FDG-PET/CT alone due to possible SUV overlap between hibernoma and liposarcoma, it is important to recognize this extremely rare lipogenic tumor for accurate diagnosis and appropriate management. |
| format | Article |
| id | doaj-art-0cfa8bce8ddf4fc7bddc030b6659efb8 |
| institution | Kabale University |
| issn | 2090-6749 2090-6757 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Orthopedics |
| spelling | doaj-art-0cfa8bce8ddf4fc7bddc030b6659efb82025-02-03T01:09:27ZengWileyCase Reports in Orthopedics2090-67492090-67572015-01-01201510.1155/2015/958690958690The Values and Limitations of FDG-PET/CT for Diagnosis of HibernomaJong Hoon Park0Koichi Ogura1Tomohiro Fujiwara2Akihito Nagano3Kunihiko Numoto4Takashi Terauchi5Akihiko Yoshida6Akira Kawai7Department of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Nuclear Medicine, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Pathology, National Cancer Center Hospital, Tokyo 104-0045, JapanDepartment of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo 104-0045, JapanHibernoma is a rare benign lipogenic tumor of brown fat that develops in a wide variety of locations. Although the features of hibernoma demonstrated by MRI resemble those of liposarcoma, recent FDG-PET/CT studies have documented higher radiotracer uptake than liposarcoma, suggesting that FDG/PET/CT is useful for differentiating hibernoma from liposarcoma. Here we report two cases of hibernoma that showed relatively lower SUVs than those reported previously, lying within the range for liposarcoma. Our findings emphasize that hibernoma needs to be included in the differential diagnosis of any fat-containing tumor showing intense accumulation by FDG-PET/CT. Although it is unlikely that such a rare condition could be reasonably diagnosed on the basis of MRI and FDG-PET/CT alone due to possible SUV overlap between hibernoma and liposarcoma, it is important to recognize this extremely rare lipogenic tumor for accurate diagnosis and appropriate management.http://dx.doi.org/10.1155/2015/958690 |
| spellingShingle | Jong Hoon Park Koichi Ogura Tomohiro Fujiwara Akihito Nagano Kunihiko Numoto Takashi Terauchi Akihiko Yoshida Akira Kawai The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma Case Reports in Orthopedics |
| title | The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma |
| title_full | The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma |
| title_fullStr | The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma |
| title_full_unstemmed | The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma |
| title_short | The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma |
| title_sort | values and limitations of fdg pet ct for diagnosis of hibernoma |
| url | http://dx.doi.org/10.1155/2015/958690 |
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