Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure

Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure

IntroductionPathological high intraocular pressure (IOP) is an important risk factor for glaucoma. The lamina cribrosa (LC) area in the optic nerve head is the initial site of optic nerve injury for glaucoma. LC deformation caused by elevated IOP will compress the retinal ganglion cells (RGC) axons...

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Bibliographic Details
Main Authors: Bochao Ma, Liu Liu, Yushu Liu, Jifeng Ren, Xiuqing Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
high intraocular pressure
lamina cribrosa
morphology
mechanical properties
RGC axons
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1574231/full
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