Effects of systemic oxytocin and beta‐3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet‐induced obese rats

Effects of systemic oxytocin and beta‐3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet‐induced obese rats

Previous studies have implicated hindbrain oxytocin (OT) receptors in the control of food intake and brown adipose tissue (BAT) thermogenesis. We recently demonstrated that hindbrain [fourth ventricle (4V)] administration of oxytocin (OT) could be used as an adjunct to drugs that directly target bet...

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Bibliographic Details
Main Authors: Jared D. Slattery, June R. Rambousek, Edison Tsui, Mackenzie K. Honeycutt, Matvey Goldberg, James L. Graham, Tomasz A. Wietecha, Tami Wolden-Hanson, Amber L. Williams, Kevin D. O’Brien, Peter J. Havel, James E. Blevins
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Endocrinology
Subjects:
obesity
brown adipose tissue (BAT)
white adipose tissue (WAT)
food intake
thermogenesis
oxytocin
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1503096/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1503096/full

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