ECM-binding properties of extracellular vesicles: advanced delivery strategies for therapeutic applications in bone and joint diseases

ECM-binding properties of extracellular vesicles: advanced delivery strategies for therapeutic applications in bone and joint diseases

Abstract Extracellular vesicles (EVs) and the extracellular matrix (ECM) are essential in maintaining bone and joint health by facilitating intercellular communication, regulating tissue processes and providing structural support. EVs with a large surface area carry diverse biomolecules to steer the...

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Bibliographic Details
Main Authors: Peng Wang, Johanna F. A. Husch, Onno J. Arntz, Peter M. van der Kraan, Fons A. J. van de Loo, Jeroen J. J. P. van den Beucken
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell Communication and Signaling
Subjects:
Bone
Extracellular vesicles
Extracellular matrix
Delivery system
Joint
Online Access:https://doi.org/10.1186/s12964-025-02156-5
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https://doi.org/10.1186/s12964-025-02156-5

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