The Efficacy of Topical Cefiderocol Treatment of Experimental Extensively Drug-Resistant <i>Pseudomonas aeruginosa</i> Keratitis Is Dependent upon the State of the Corneal Epithelium

The Efficacy of Topical Cefiderocol Treatment of Experimental Extensively Drug-Resistant <i>Pseudomonas aeruginosa</i> Keratitis Is Dependent upon the State of the Corneal Epithelium

<b>Background:</b> An overlooked factor in the efficacy of topical antibiotics to treat bacterial keratitis is the state of the corneal epithelium. Recently, we evaluated topical cefiderocol for the treatment of extensively drug-resistant (XDR) <i>Pseudomonas aeruginosa</i> (...

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Bibliographic Details
Main Authors: Eric G. Romanowski, Jonathan B. Mandell, Vishal Jhanji, Robert M.Q. Shanks
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Antibiotics
Subjects:
<i>Pseudomonas aeruginosa</i>
keratitis
corneal epithelium
antibiotic penetration
extensively drug-resistant
cefiderocol
Online Access:https://www.mdpi.com/2079-6382/13/10/979
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