Nonsurgical Management of Nifedipine Induced Gingival Overgrowth

Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this...

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Main Authors: George Sam, Staly Chakkalakkal Sebastian
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2014/741402
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author George Sam
Staly Chakkalakkal Sebastian
author_facet George Sam
Staly Chakkalakkal Sebastian
author_sort George Sam
collection DOAJ
description Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosporin. The frequency of gingival enlargement associated with chronic nifedipine therapy remains controversial. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. Although gingival inflammation is considered a primary requisite in their development, few cases with minimal or no plaque induced gingival inflammation have also been reported. A case report of gingival overgrowth induced by nifedipine in a patient with good oral hygiene and its nonsurgical management with drug substitution is discussed in this case report.
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spelling doaj-art-0be49feee53940e3bcfbffe20f75f0b62025-02-03T05:52:51ZengWileyCase Reports in Dentistry2090-64472090-64552014-01-01201410.1155/2014/741402741402Nonsurgical Management of Nifedipine Induced Gingival OvergrowthGeorge Sam0Staly Chakkalakkal Sebastian1Department of Periodontics, Government Dental College, Kottayam, Kerala, IndiaObstetrics and Gynaecology, Kerala Institute of Medical Sciences, Trivandrum, Kerala, IndiaDrug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosporin. The frequency of gingival enlargement associated with chronic nifedipine therapy remains controversial. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. Although gingival inflammation is considered a primary requisite in their development, few cases with minimal or no plaque induced gingival inflammation have also been reported. A case report of gingival overgrowth induced by nifedipine in a patient with good oral hygiene and its nonsurgical management with drug substitution is discussed in this case report.http://dx.doi.org/10.1155/2014/741402
spellingShingle George Sam
Staly Chakkalakkal Sebastian
Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
Case Reports in Dentistry
title Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
title_full Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
title_fullStr Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
title_full_unstemmed Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
title_short Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
title_sort nonsurgical management of nifedipine induced gingival overgrowth
url http://dx.doi.org/10.1155/2014/741402
work_keys_str_mv AT georgesam nonsurgicalmanagementofnifedipineinducedgingivalovergrowth
AT stalychakkalakkalsebastian nonsurgicalmanagementofnifedipineinducedgingivalovergrowth