Nonsurgical Management of Nifedipine Induced Gingival Overgrowth
Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this...
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Language: | English |
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Wiley
2014-01-01
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Series: | Case Reports in Dentistry |
Online Access: | http://dx.doi.org/10.1155/2014/741402 |
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author | George Sam Staly Chakkalakkal Sebastian |
author_facet | George Sam Staly Chakkalakkal Sebastian |
author_sort | George Sam |
collection | DOAJ |
description | Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosporin. The frequency of gingival enlargement associated with chronic nifedipine therapy remains controversial. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. Although gingival inflammation is considered a primary requisite in their development, few cases with minimal or no plaque induced gingival inflammation have also been reported. A case report of gingival overgrowth induced by nifedipine in a patient with good oral hygiene and its nonsurgical management with drug substitution is discussed in this case report. |
format | Article |
id | doaj-art-0be49feee53940e3bcfbffe20f75f0b6 |
institution | Kabale University |
issn | 2090-6447 2090-6455 |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Dentistry |
spelling | doaj-art-0be49feee53940e3bcfbffe20f75f0b62025-02-03T05:52:51ZengWileyCase Reports in Dentistry2090-64472090-64552014-01-01201410.1155/2014/741402741402Nonsurgical Management of Nifedipine Induced Gingival OvergrowthGeorge Sam0Staly Chakkalakkal Sebastian1Department of Periodontics, Government Dental College, Kottayam, Kerala, IndiaObstetrics and Gynaecology, Kerala Institute of Medical Sciences, Trivandrum, Kerala, IndiaDrug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosporin. The frequency of gingival enlargement associated with chronic nifedipine therapy remains controversial. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. Although gingival inflammation is considered a primary requisite in their development, few cases with minimal or no plaque induced gingival inflammation have also been reported. A case report of gingival overgrowth induced by nifedipine in a patient with good oral hygiene and its nonsurgical management with drug substitution is discussed in this case report.http://dx.doi.org/10.1155/2014/741402 |
spellingShingle | George Sam Staly Chakkalakkal Sebastian Nonsurgical Management of Nifedipine Induced Gingival Overgrowth Case Reports in Dentistry |
title | Nonsurgical Management of Nifedipine Induced Gingival Overgrowth |
title_full | Nonsurgical Management of Nifedipine Induced Gingival Overgrowth |
title_fullStr | Nonsurgical Management of Nifedipine Induced Gingival Overgrowth |
title_full_unstemmed | Nonsurgical Management of Nifedipine Induced Gingival Overgrowth |
title_short | Nonsurgical Management of Nifedipine Induced Gingival Overgrowth |
title_sort | nonsurgical management of nifedipine induced gingival overgrowth |
url | http://dx.doi.org/10.1155/2014/741402 |
work_keys_str_mv | AT georgesam nonsurgicalmanagementofnifedipineinducedgingivalovergrowth AT stalychakkalakkalsebastian nonsurgicalmanagementofnifedipineinducedgingivalovergrowth |