Omission of dexamethasone in paclitaxel premedication regimens: protocol of the multicentre, randomised, non-inferiority DEXASTOP trial

Omission of dexamethasone in paclitaxel premedication regimens: protocol of the multicentre, randomised, non-inferiority DEXASTOP trial

Introduction Standard premedication for paclitaxel-based chemotherapy includes dexamethasone and an histamine 1-antagonist to prevent hypersensitivity reactions (HSRs). However, the pharmacological rationale for dexamethasone is limited, and its use is associated with adverse effects such as hypergl...

Full description

Saved in:
Bibliographic Details
Main Authors: Birgit C P Koch, Virgil A S H Dalm, Leontine E A M M Spierings, Michiel Zietse, Luuk C Aalders, Nikki De Rouw, Wouter Dercksen, Frederick W Thielen, Leni van Doorn, Roelof W F van Leeuwen
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/4/e102770.full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://bmjopen.bmj.com/content/15/4/e102770.full

Similar Items