Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes

Plant-based oils have a long history of use as insect repellents. In an earlier study, we showed that in a 10% concentration, geraniol, 2-phenylethl propionate, and the plant-based essential oils clove and cinnamon effectively protected from mosquito bites for over 60 min. To expand on this study, w...

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Main Authors: April D. Lopez, Sophie Whyms, Hailey A. Luker, Claudia J. Galvan, F. Omar Holguin, Immo A. Hansen
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Insects
Subjects:
Online Access:https://www.mdpi.com/2075-4450/16/1/51
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author April D. Lopez
Sophie Whyms
Hailey A. Luker
Claudia J. Galvan
F. Omar Holguin
Immo A. Hansen
author_facet April D. Lopez
Sophie Whyms
Hailey A. Luker
Claudia J. Galvan
F. Omar Holguin
Immo A. Hansen
author_sort April D. Lopez
collection DOAJ
description Plant-based oils have a long history of use as insect repellents. In an earlier study, we showed that in a 10% concentration, geraniol, 2-phenylethl propionate, and the plant-based essential oils clove and cinnamon effectively protected from mosquito bites for over 60 min. To expand on this study, we reanalyzed our GC–MS data to identify the short organic constituents of these oils. We then used an arm-in-cage assay to test the repellency of different concentrations and combinations of these oils and pure compounds. We found a sigmoidal relationship between the complete protection time from mosquito bites and the concentration of these oils. The complete protection times we recorded for combinations of these oils suggest an absence of additive effects. The results of this study can inform the development of novel, effective, and plant-based insect repellents.
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series Insects
spelling doaj-art-0bab0a1ba47e4a4c840d3f9ad0127b282025-01-24T13:35:43ZengMDPI AGInsects2075-44502025-01-011615110.3390/insects16010051Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> MosquitoesApril D. Lopez0Sophie Whyms1Hailey A. Luker2Claudia J. Galvan3F. Omar Holguin4Immo A. Hansen5Department of Biology, New Mexico State University, Las Cruces, NM 88003, USANatPro Centre, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, 2 Dublin, IrelandDepartment of Biology, New Mexico State University, Las Cruces, NM 88003, USADepartment of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM 88003, USADepartment of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM 88003, USADepartment of Biology, New Mexico State University, Las Cruces, NM 88003, USAPlant-based oils have a long history of use as insect repellents. In an earlier study, we showed that in a 10% concentration, geraniol, 2-phenylethl propionate, and the plant-based essential oils clove and cinnamon effectively protected from mosquito bites for over 60 min. To expand on this study, we reanalyzed our GC–MS data to identify the short organic constituents of these oils. We then used an arm-in-cage assay to test the repellency of different concentrations and combinations of these oils and pure compounds. We found a sigmoidal relationship between the complete protection time from mosquito bites and the concentration of these oils. The complete protection times we recorded for combinations of these oils suggest an absence of additive effects. The results of this study can inform the development of novel, effective, and plant-based insect repellents.https://www.mdpi.com/2075-4450/16/1/51repellentessential oilsconcentrationsmixturesarm-in-cageclove
spellingShingle April D. Lopez
Sophie Whyms
Hailey A. Luker
Claudia J. Galvan
F. Omar Holguin
Immo A. Hansen
Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes
Insects
repellent
essential oils
concentrations
mixtures
arm-in-cage
clove
title Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes
title_full Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes
title_fullStr Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes
title_full_unstemmed Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes
title_short Repellency of Essential Oils and Plant-Derived Compounds Against <i>Aedes aegypti</i> Mosquitoes
title_sort repellency of essential oils and plant derived compounds against i aedes aegypti i mosquitoes
topic repellent
essential oils
concentrations
mixtures
arm-in-cage
clove
url https://www.mdpi.com/2075-4450/16/1/51
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