spCLUE: a contrastive learning approach to unified spatial transcriptomics analysis across single-slice and multi-slice data
Abstract Advances in spatial transcriptomics demand new tools to integrate data across tissue slices and identify consistent spatial domains. We introduce spCLUE, a comprehensive framework combining multi-view graph network, contrastive learning, attention mechanisms, and a batch prompting module to...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03636-0 |
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