Targeting adenosine enhances immunotherapy in MSS colorectal cancer with EGFRvIII mutation

Targeting adenosine enhances immunotherapy in MSS colorectal cancer with EGFRvIII mutation

Background Patients with microsatellite stable (MSS) colorectal cancer (CRC) often display resistance to immunotherapy. Epidermal growth factor receptor (EGFR)-targeted therapies have shown potential in enhancing immunotherapy, yet clinical benefits remain unfulfilled, which may relate to inadequate...

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Main Authors: Jing Wu, Yang Zhao, Min Shi, Yong Li, Yu Jiang, Fei Sun, Jianjun Peng, Jiao Wang, Qiong Huang, Na Huang, Yawen Wang, Yulu Shi, Xiaoxiang Rong, Wangjun Liao, Chunlin Wang, Fangzhen Yao, Chunting Zeng, Bishan Liang, Shaowei Li, Qijing Wu, Zhiqi Yao, Chunhui Gu, Yujing Tan
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/2/e010126.full
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https://jitc.bmj.com/content/13/2/e010126.full

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