Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort.

Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort.

<h4>Objectives</h4>There are significant geographical differences in the prevalence and incidence of celiac disease that cannot be explained by HLA alone. More than 40 loci outside of the HLA region have been associated with celiac disease. We investigated the roles of these non-HLA gene...

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Main Authors: Ashok Sharma, Xiang Liu, David Hadley, William Hagopian, Edwin Liu, Wei-Min Chen, Suna Onengut-Gumuscu, Ville Simell, Marian Rewers, Anette-G Ziegler, Åke Lernmark, Olli Simell, Jorma Toppari, Jeffrey P Krischer, Beena Akolkar, Stephen S Rich, Daniel Agardh, Jin-Xiong She, TEDDY Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0152476&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0152476&type=printable

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