Analytical techniques for nucleic acid and protein detection with single-molecule sensitivity

Abstract Nucleic acids and proteins serve as crucial biomarkers used in the diagnosis, prognosis and therapy monitoring across various diseases. Traditionally, these biomarkers are identified at an ensemble level following the amplification of target or signaling molecules. However, these methods ha...

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Bibliographic Details
Main Authors: Soochul Shin, Juyoung Kim, Eunho Song, Sun Han, Sungchul Hohng
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01453-w
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