Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study
Background. Several predictors have been shown to be independently associated with chronic postsurgical pain for gastrointestinal surgery, but few studies have investigated the factors associated with acute postsurgical pain (APSP). The aim of this study was to identify the predictors of APSP intens...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2021/6668152 |
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| author | Qing-Ren Liu Mu-Huo Ji Yu-Chen Dai Xing-Bing Sun Cheng-Mao Zhou Xiao-Dong Qiu Jian-Jun Yang |
| author_facet | Qing-Ren Liu Mu-Huo Ji Yu-Chen Dai Xing-Bing Sun Cheng-Mao Zhou Xiao-Dong Qiu Jian-Jun Yang |
| author_sort | Qing-Ren Liu |
| collection | DOAJ |
| description | Background. Several predictors have been shown to be independently associated with chronic postsurgical pain for gastrointestinal surgery, but few studies have investigated the factors associated with acute postsurgical pain (APSP). The aim of this study was to identify the predictors of APSP intensity and severity through investigating demographic, psychological, and clinical variables. Methods. We performed a prospective cohort study of 282 patients undergoing gastrointestinal surgery to analyze the predictors of APSP. Psychological questionnaires were assessed 1 day before surgery. Meanwhile, demographic characteristics and perioperative data were collected. The primary outcomes are APSP intensity assessed by numeric rating scale (NRS) and APSP severity defined as a clinically meaningful pain when NRS ≥4. The predictors for APSP intensity and severity were determined using multiple linear regression and multivariate logistic regression, respectively. Results. 112 patients (39.7%) reported a clinically meaningful pain during the first 24 hours postoperatively. Oral morphine milligram equivalent (MME) consumption (β 0.05, 95% CI 0.03–0.07, p<0.001), preoperative anxiety (β 0.12, 95% CI 0.08–0.15, p<0.001), and expected postsurgical pain intensity (β 0.12, 95% CI 0.06–0.18, p<0.001) were positively associated with APSP intensity. Furthermore, MME consumption (OR 1.15, 95% CI 1.10–1.21, p<0.001), preoperative anxiety (OR 1.33, 95% CI 1.21–1.46, p<0.001), and expected postsurgical pain intensity (OR 1.36, 95% CI 1.17–1.57, p<0.001) were independently associated with APSP severity. Conclusion. These results suggested that the predictors for APSP intensity following gastrointestinal surgery included analgesic consumption, preoperative anxiety, and expected postsurgical pain, which were also the risk factors for APSP severity. |
| format | Article |
| id | doaj-art-0b66f91d3d5c4ca8a79adb5aa19cdb59 |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-0b66f91d3d5c4ca8a79adb5aa19cdb592025-02-03T05:49:51ZengWileyPain Research and Management1203-67651918-15232021-01-01202110.1155/2021/66681526668152Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort StudyQing-Ren Liu0Mu-Huo Ji1Yu-Chen Dai2Xing-Bing Sun3Cheng-Mao Zhou4Xiao-Dong Qiu5Jian-Jun Yang6School of Medicine, Southeast University, Nanjing 210009, ChinaDepartment of Anesthesiology, The Second Affiliated Hospital, Nanjing Medical University, Nanjing 210011, ChinaDepartment of Anesthesiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, ChinaDepartment of Anesthesiology, Xishan People’s Hospital of Wuxi City, Wuxi 214105, ChinaDepartment of Anesthesiology,Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, ChinaDepartment of Anesthesiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, ChinaSchool of Medicine, Southeast University, Nanjing 210009, ChinaBackground. Several predictors have been shown to be independently associated with chronic postsurgical pain for gastrointestinal surgery, but few studies have investigated the factors associated with acute postsurgical pain (APSP). The aim of this study was to identify the predictors of APSP intensity and severity through investigating demographic, psychological, and clinical variables. Methods. We performed a prospective cohort study of 282 patients undergoing gastrointestinal surgery to analyze the predictors of APSP. Psychological questionnaires were assessed 1 day before surgery. Meanwhile, demographic characteristics and perioperative data were collected. The primary outcomes are APSP intensity assessed by numeric rating scale (NRS) and APSP severity defined as a clinically meaningful pain when NRS ≥4. The predictors for APSP intensity and severity were determined using multiple linear regression and multivariate logistic regression, respectively. Results. 112 patients (39.7%) reported a clinically meaningful pain during the first 24 hours postoperatively. Oral morphine milligram equivalent (MME) consumption (β 0.05, 95% CI 0.03–0.07, p<0.001), preoperative anxiety (β 0.12, 95% CI 0.08–0.15, p<0.001), and expected postsurgical pain intensity (β 0.12, 95% CI 0.06–0.18, p<0.001) were positively associated with APSP intensity. Furthermore, MME consumption (OR 1.15, 95% CI 1.10–1.21, p<0.001), preoperative anxiety (OR 1.33, 95% CI 1.21–1.46, p<0.001), and expected postsurgical pain intensity (OR 1.36, 95% CI 1.17–1.57, p<0.001) were independently associated with APSP severity. Conclusion. These results suggested that the predictors for APSP intensity following gastrointestinal surgery included analgesic consumption, preoperative anxiety, and expected postsurgical pain, which were also the risk factors for APSP severity.http://dx.doi.org/10.1155/2021/6668152 |
| spellingShingle | Qing-Ren Liu Mu-Huo Ji Yu-Chen Dai Xing-Bing Sun Cheng-Mao Zhou Xiao-Dong Qiu Jian-Jun Yang Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study Pain Research and Management |
| title | Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study |
| title_full | Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study |
| title_fullStr | Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study |
| title_full_unstemmed | Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study |
| title_short | Predictors of Acute Postsurgical Pain following Gastrointestinal Surgery: A Prospective Cohort Study |
| title_sort | predictors of acute postsurgical pain following gastrointestinal surgery a prospective cohort study |
| url | http://dx.doi.org/10.1155/2021/6668152 |
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