Drosophila Cul3 contributes to Diap2-mediated innate immune signaling for antimicrobial defense

Drosophila Cul3 contributes to Diap2-mediated innate immune signaling for antimicrobial defense

The host antimicrobial immune response relies on a complex interplay of molecular mechanisms to effectively combat microbial infections. Herein, we investigate the functional role of Cullin-3 (Cul3), one critical constituent of Cullin-RING ubiquitin ligases, in the Drosophila melanogaster (fruit fly...

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Bibliographic Details
Main Authors: Fanrui Kong, Zixuan Wang, Chuchu Zhang, Yihua Xiao, Muhammad Abdul Rehman Saeed, Weini Li, Akira Goto, Qingshuang Cai, Shanming Ji
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:hLife
Subjects:
Cullin-3 (Cul3)
death-associated inhibitor of apoptosis 2 (Diap2)
death-related ced-3/Nedd2-like caspase (Dredd) ubiquitination
antimicrobial immune defense
Drosophila melanogaster
Online Access:http://www.sciencedirect.com/science/article/pii/S2949928324000841
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http://www.sciencedirect.com/science/article/pii/S2949928324000841

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