D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint

Abstract Background Targeting glucose uptake by glucose transporter (GLUT) inhibitors is a therapeutic opportunity, but efforts on GLUT inhibitors have not been successful in the clinic and the underlying mechanism remains unclear. We aim to identify the key metabolic changes responsible for cancer...

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Bibliographic Details
Main Authors: Cheng-E Tu, Yong-Feng Liu, Hong-Wei Liu, Chun-Mei Jiao, Quentin Liu, Mien-Chie Hung, Peng Li, Xiang-Bo Wan, Xin-Juan Fan, Yun-Long Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Hematology & Oncology
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Online Access:https://doi.org/10.1186/s13045-024-01655-1
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