Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells

Rab11b is necessary for mitochondrial integrity and function in gut epithelial cells

IntroductionThe RAB11 family of small GTPases are intracellular regulators of membrane and vesicular trafficking. We recently reported that RAB11A and RAB11B redundantly regulate spindle dynamics in dividing gut epithelial cells. However, in contrast to the well-studied RAB11A functions in transport...

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Main Authors: Ivor Joseph, Jiangmeng Han, Jared Bianchi-Smak, Jiaxing Yang, Jagannatham Naidu Bhupana, Juan Flores, Jack Delucia, Tracy S. Tran, James R. Goldenring, Edward M. Bonder, Nan Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Rab11
mitochondria
Paneth cell
proteomics
intestine
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1498902/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1498902/full

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