TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis

TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis

Hepatocellular carcinoma (HCC) is a highly lethal and heterogeneous tumor driven by the dysregulation of multiple genes. Tubulin tyrosine ligase-like 4 (TTLL4) has been linked to tumor progression, but its specific role in HCC pathogenesis remains unclear. RNA sequencing data, somatic mutation profi...

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Bibliographic Details
Main Authors: Zeping He, Desheng Chen, Lei Li, Shanbao Li, Fangbin Song, Jinfeng Cai, Xueyan Guo, Yaohao Luo, Xinshuai Wang, Zeping Chen, Junming Xu
Format: Article
Language:English
Published: AIP Publishing LLC 2025-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0267938
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