A comprehensive review on roles of electrochemical approaches in drug delivery

The advancement of drug delivery systems (DDS) has significantly enhanced the efficacy and safety of therapeutic agents addressing limitations such as poor bioavailability and non-specific distribution associated with traditional methods. This article provides a comprehensive review of the role of e...

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Main Authors: Ali R. Jalalvand, Mohammad Mehdi Karami
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Sensing and Bio-Sensing Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221418042500008X
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author Ali R. Jalalvand
Mohammad Mehdi Karami
author_facet Ali R. Jalalvand
Mohammad Mehdi Karami
author_sort Ali R. Jalalvand
collection DOAJ
description The advancement of drug delivery systems (DDS) has significantly enhanced the efficacy and safety of therapeutic agents addressing limitations such as poor bioavailability and non-specific distribution associated with traditional methods. This article provides a comprehensive review of the role of electrochemical approaches in DDS, highlighting their precision, minimally invasive nature and ability to provide targeted and localized therapy. Electrochemical methods including voltammetry, amperometry and potentiometry offer unparalleled control over drug release kinetics and distribution, presenting significant advantages for the treatment of chronic and complex diseases like cancer, cardiovascular disorders, and neurological conditions. The integration of biotechnology, materials science and nanotechnology has led to the development of sophisticated DDS that respond to specific biological signals. This review discusses the fundamental principles of electrochemistry, various electrochemical techniques, and their applications in DDS alongside current innovations and future research directions in the field. The potential of electrochemical approaches to revolutionize drug delivery by providing precise, controlled, and targeted therapeutic interventions is emphasized, underscoring their growing importance in personalized medicine and future biomedical applications.
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spelling doaj-art-0a1fbfef8e13471f81c759163ab40df32025-01-27T04:21:56ZengElsevierSensing and Bio-Sensing Research2214-18042025-02-0147100742A comprehensive review on roles of electrochemical approaches in drug deliveryAli R. Jalalvand0Mohammad Mehdi Karami1Corresponding author.; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, IranPharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, IranThe advancement of drug delivery systems (DDS) has significantly enhanced the efficacy and safety of therapeutic agents addressing limitations such as poor bioavailability and non-specific distribution associated with traditional methods. This article provides a comprehensive review of the role of electrochemical approaches in DDS, highlighting their precision, minimally invasive nature and ability to provide targeted and localized therapy. Electrochemical methods including voltammetry, amperometry and potentiometry offer unparalleled control over drug release kinetics and distribution, presenting significant advantages for the treatment of chronic and complex diseases like cancer, cardiovascular disorders, and neurological conditions. The integration of biotechnology, materials science and nanotechnology has led to the development of sophisticated DDS that respond to specific biological signals. This review discusses the fundamental principles of electrochemistry, various electrochemical techniques, and their applications in DDS alongside current innovations and future research directions in the field. The potential of electrochemical approaches to revolutionize drug delivery by providing precise, controlled, and targeted therapeutic interventions is emphasized, underscoring their growing importance in personalized medicine and future biomedical applications.http://www.sciencedirect.com/science/article/pii/S221418042500008XElectrochemical methodsDrug deliveryBiomedical applications
spellingShingle Ali R. Jalalvand
Mohammad Mehdi Karami
A comprehensive review on roles of electrochemical approaches in drug delivery
Sensing and Bio-Sensing Research
Electrochemical methods
Drug delivery
Biomedical applications
title A comprehensive review on roles of electrochemical approaches in drug delivery
title_full A comprehensive review on roles of electrochemical approaches in drug delivery
title_fullStr A comprehensive review on roles of electrochemical approaches in drug delivery
title_full_unstemmed A comprehensive review on roles of electrochemical approaches in drug delivery
title_short A comprehensive review on roles of electrochemical approaches in drug delivery
title_sort comprehensive review on roles of electrochemical approaches in drug delivery
topic Electrochemical methods
Drug delivery
Biomedical applications
url http://www.sciencedirect.com/science/article/pii/S221418042500008X
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