Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology

Background: Nasal and paranasal abnormalities frequently represent the primary observations in the otorhinolaryngology domain. Thorough clinical evaluation and radiological methodologies aid in establishing a preliminary diagnosis; however, histopathological examination (HPE) remains indispensable f...

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Main Authors: Soumya Sahu, Garima Malpani, Amit V. Varma, Kamal Malukani, Bela Sharda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-04-01
Series:MGM Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.4103/mgmj.mgmj_26_24
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author Soumya Sahu
Garima Malpani
Amit V. Varma
Kamal Malukani
Bela Sharda
author_facet Soumya Sahu
Garima Malpani
Amit V. Varma
Kamal Malukani
Bela Sharda
author_sort Soumya Sahu
collection DOAJ
description Background: Nasal and paranasal abnormalities frequently represent the primary observations in the otorhinolaryngology domain. Thorough clinical evaluation and radiological methodologies aid in establishing a preliminary diagnosis; however, histopathological examination (HPE) remains indispensable for confirming a definitive diagnosis. The objective is to determine the demographic breakdown of patients exhibiting sinonasal lesions and to evaluate and correlate clinical and radiological observations with histopathological diagnoses. Materials and Methods: This ambispective observational study involved 128 sinonasal lesions diagnosed via histopathology spanning 3 years (2020–2023). All pertinent clinical radiological observations were recorded, and tissue samples underwent staining with hematoxylin and eosin (H&E), special stains, and immunohistochemistry (IHC) when necessary. The collected data were organized into tables, and statistical analyses were conducted. Results: Among the 128 cases examined, 98 (76.56%) were identified as non-neoplastic lesions, 14 (10.93%) as benign neoplasms, and 16 (12.50%) as malignant lesions through HPE. The male-to-female ratio stood at 1.2:1. The highest number of cases was observed within the age bracket of 21–40 years. Nasal obstruction emerged as the predominant symptom, accounting for 46 (35.93%) cases. Conclusion: A broad range of lesions can impact the sinonasal tract. While clinical and radiological characteristics may exhibit similarities, histopathology is the ultimate standard for confirming a definitive diagnosis.
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spelling doaj-art-09e286c92e43494ca40aa95598f9da922025-01-25T10:19:23ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622024-04-0111219520010.4103/mgmj.mgmj_26_24Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiologySoumya SahuGarima MalpaniAmit V. VarmaKamal MalukaniBela ShardaBackground: Nasal and paranasal abnormalities frequently represent the primary observations in the otorhinolaryngology domain. Thorough clinical evaluation and radiological methodologies aid in establishing a preliminary diagnosis; however, histopathological examination (HPE) remains indispensable for confirming a definitive diagnosis. The objective is to determine the demographic breakdown of patients exhibiting sinonasal lesions and to evaluate and correlate clinical and radiological observations with histopathological diagnoses. Materials and Methods: This ambispective observational study involved 128 sinonasal lesions diagnosed via histopathology spanning 3 years (2020–2023). All pertinent clinical radiological observations were recorded, and tissue samples underwent staining with hematoxylin and eosin (H&E), special stains, and immunohistochemistry (IHC) when necessary. The collected data were organized into tables, and statistical analyses were conducted. Results: Among the 128 cases examined, 98 (76.56%) were identified as non-neoplastic lesions, 14 (10.93%) as benign neoplasms, and 16 (12.50%) as malignant lesions through HPE. The male-to-female ratio stood at 1.2:1. The highest number of cases was observed within the age bracket of 21–40 years. Nasal obstruction emerged as the predominant symptom, accounting for 46 (35.93%) cases. Conclusion: A broad range of lesions can impact the sinonasal tract. While clinical and radiological characteristics may exhibit similarities, histopathology is the ultimate standard for confirming a definitive diagnosis.https://doi.org/10.4103/mgmj.mgmj_26_24histopathologyneoplasticpolypsinonasal lesions
spellingShingle Soumya Sahu
Garima Malpani
Amit V. Varma
Kamal Malukani
Bela Sharda
Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
MGM Journal of Medical Sciences
histopathology
neoplastic
polyp
sinonasal lesions
title Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
title_full Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
title_fullStr Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
title_full_unstemmed Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
title_short Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
title_sort clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
topic histopathology
neoplastic
polyp
sinonasal lesions
url https://doi.org/10.4103/mgmj.mgmj_26_24
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AT garimamalpani clinicopathologicalstudyofmassesofnasalcavityandparanasalsinusesanditscorrelationwithradiology
AT amitvvarma clinicopathologicalstudyofmassesofnasalcavityandparanasalsinusesanditscorrelationwithradiology
AT kamalmalukani clinicopathologicalstudyofmassesofnasalcavityandparanasalsinusesanditscorrelationwithradiology
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