Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology
Background: Nasal and paranasal abnormalities frequently represent the primary observations in the otorhinolaryngology domain. Thorough clinical evaluation and radiological methodologies aid in establishing a preliminary diagnosis; however, histopathological examination (HPE) remains indispensable f...
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Language: | English |
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Wolters Kluwer Medknow Publications
2024-04-01
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Series: | MGM Journal of Medical Sciences |
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Online Access: | https://doi.org/10.4103/mgmj.mgmj_26_24 |
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author | Soumya Sahu Garima Malpani Amit V. Varma Kamal Malukani Bela Sharda |
author_facet | Soumya Sahu Garima Malpani Amit V. Varma Kamal Malukani Bela Sharda |
author_sort | Soumya Sahu |
collection | DOAJ |
description | Background: Nasal and paranasal abnormalities frequently represent the primary observations in the otorhinolaryngology domain. Thorough clinical evaluation and radiological methodologies aid in establishing a preliminary diagnosis; however, histopathological examination (HPE) remains indispensable for confirming a definitive diagnosis. The objective is to determine the demographic breakdown of patients exhibiting sinonasal lesions and to evaluate and correlate clinical and radiological observations with histopathological diagnoses. Materials and Methods: This ambispective observational study involved 128 sinonasal lesions diagnosed via histopathology spanning 3 years (2020–2023). All pertinent clinical radiological observations were recorded, and tissue samples underwent staining with hematoxylin and eosin (H&E), special stains, and immunohistochemistry (IHC) when necessary. The collected data were organized into tables, and statistical analyses were conducted. Results: Among the 128 cases examined, 98 (76.56%) were identified as non-neoplastic lesions, 14 (10.93%) as benign neoplasms, and 16 (12.50%) as malignant lesions through HPE. The male-to-female ratio stood at 1.2:1. The highest number of cases was observed within the age bracket of 21–40 years. Nasal obstruction emerged as the predominant symptom, accounting for 46 (35.93%) cases. Conclusion: A broad range of lesions can impact the sinonasal tract. While clinical and radiological characteristics may exhibit similarities, histopathology is the ultimate standard for confirming a definitive diagnosis. |
format | Article |
id | doaj-art-09e286c92e43494ca40aa95598f9da92 |
institution | Kabale University |
issn | 2347-7946 2347-7962 |
language | English |
publishDate | 2024-04-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | MGM Journal of Medical Sciences |
spelling | doaj-art-09e286c92e43494ca40aa95598f9da922025-01-25T10:19:23ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622024-04-0111219520010.4103/mgmj.mgmj_26_24Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiologySoumya SahuGarima MalpaniAmit V. VarmaKamal MalukaniBela ShardaBackground: Nasal and paranasal abnormalities frequently represent the primary observations in the otorhinolaryngology domain. Thorough clinical evaluation and radiological methodologies aid in establishing a preliminary diagnosis; however, histopathological examination (HPE) remains indispensable for confirming a definitive diagnosis. The objective is to determine the demographic breakdown of patients exhibiting sinonasal lesions and to evaluate and correlate clinical and radiological observations with histopathological diagnoses. Materials and Methods: This ambispective observational study involved 128 sinonasal lesions diagnosed via histopathology spanning 3 years (2020–2023). All pertinent clinical radiological observations were recorded, and tissue samples underwent staining with hematoxylin and eosin (H&E), special stains, and immunohistochemistry (IHC) when necessary. The collected data were organized into tables, and statistical analyses were conducted. Results: Among the 128 cases examined, 98 (76.56%) were identified as non-neoplastic lesions, 14 (10.93%) as benign neoplasms, and 16 (12.50%) as malignant lesions through HPE. The male-to-female ratio stood at 1.2:1. The highest number of cases was observed within the age bracket of 21–40 years. Nasal obstruction emerged as the predominant symptom, accounting for 46 (35.93%) cases. Conclusion: A broad range of lesions can impact the sinonasal tract. While clinical and radiological characteristics may exhibit similarities, histopathology is the ultimate standard for confirming a definitive diagnosis.https://doi.org/10.4103/mgmj.mgmj_26_24histopathologyneoplasticpolypsinonasal lesions |
spellingShingle | Soumya Sahu Garima Malpani Amit V. Varma Kamal Malukani Bela Sharda Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology MGM Journal of Medical Sciences histopathology neoplastic polyp sinonasal lesions |
title | Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology |
title_full | Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology |
title_fullStr | Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology |
title_full_unstemmed | Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology |
title_short | Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology |
title_sort | clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology |
topic | histopathology neoplastic polyp sinonasal lesions |
url | https://doi.org/10.4103/mgmj.mgmj_26_24 |
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