SAP30, a novel autophagy regulatory gene in neuroblastoma

SAP30, a novel autophagy regulatory gene in neuroblastoma

Neuroblastoma (NB), a devastating pediatric cancer originating from neural crest cells crucial for nervous system development, poses a significant therapeutic challenge. Despite chemotherapy being the primary treatment, approximately 70% of high-risk NB cases develop resistance. Autophagy is vital f...

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Bibliographic Details
Main Authors: Anup S. Pathania, Anjana Murugan, Areem Zahid, Haritha Chava, Don W. Coulter, George A. Calin, Kishore B. Challagundla
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Therapy: Oncology
Subjects:
MT: Novel therapeutic targets and biomarker development special issue
neuroblastoma
autophagy
SAP30
autophagosome
chemotherapy response
Online Access:http://www.sciencedirect.com/science/article/pii/S2950329924001589
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