Relationship Between the Salivary Microbiome and Oral Malodor Metabolites in Older Thai Individuals with Periodontitis and the Cytotoxic Effects of Malodor Compounds on Human Oral Squamous Carcinoma (HSC-4) Cells

Relationship Between the Salivary Microbiome and Oral Malodor Metabolites in Older Thai Individuals with Periodontitis and the Cytotoxic Effects of Malodor Compounds on Human Oral Squamous Carcinoma (HSC-4) Cells

<b>Background/Objectives</b>: Halitosis is primarily caused by the activity of oral microorganisms. In this study, we employed metagenomic sequencing and metabolomic approaches to investigate the differences in salivary microbiota and metabolite profiles between individuals with halitosi...

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Main Authors: Witsanu Srila, Kritsana Sripilai, Thunwa Binlateh, Peungchaleoy Thammanichanon, Watcharaphol Tiskratok, Parinya Noisa, Paiboon Jitprasertwong
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Dentistry Journal
Subjects:
halitosis
periodontitis
salivary microbiome
oral malodorous compound
salivary metabolomics
human oral squamous carcinoma cells
Online Access:https://www.mdpi.com/2304-6767/13/1/36
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