Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study
Pulse pressure variation can predict fluid responsiveness in strict applicability conditions. The purpose of this study was to describe the clinical applicability of pulse pressure variation during episodes of patient hemodynamic instability in the intensive care unit. We conducted a five-day, seven...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Critical Care Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/7162190 |
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| author | Bertrand Delannoy Florent Wallet Delphine Maucort-Boulch Mathieu Page Mahmoud Kaaki Mathieu Schoeffler Brenton Alexander Olivier Desebbe |
| author_facet | Bertrand Delannoy Florent Wallet Delphine Maucort-Boulch Mathieu Page Mahmoud Kaaki Mathieu Schoeffler Brenton Alexander Olivier Desebbe |
| author_sort | Bertrand Delannoy |
| collection | DOAJ |
| description | Pulse pressure variation can predict fluid responsiveness in strict applicability conditions. The purpose of this study was to describe the clinical applicability of pulse pressure variation during episodes of patient hemodynamic instability in the intensive care unit. We conducted a five-day, seven-center prospective study that included patients presenting with an unstable hemodynamic event. The six predefined inclusion criteria for pulse pressure variation applicability were as follows: mechanical ventilation, tidal volume >7 mL/kg, sinus rhythm, no spontaneous breath, heart rate/respiratory rate ratio >3.6, absence of right ventricular dysfunction, or severe valvulopathy. Seventy-three patients presented at least one unstable hemodynamic event, with a total of 163 unstable hemodynamic events. The six predefined criteria for the applicability of pulse pressure variation were completely present in only 7% of these. This data indicates that PPV should only be used alongside a strong understanding of the relevant physiology and applicability criteria. Although these exclusion criteria appear to be profound, they likely represent an absolute contraindication of use for only a minority of critical care patients. |
| format | Article |
| id | doaj-art-0950faf6b29d443eb64f108adb081a05 |
| institution | Kabale University |
| issn | 2090-1305 2090-1313 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
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| series | Critical Care Research and Practice |
| spelling | doaj-art-0950faf6b29d443eb64f108adb081a052025-02-03T06:15:12ZengWileyCritical Care Research and Practice2090-13052090-13132016-01-01201610.1155/2016/71621907162190Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter StudyBertrand Delannoy0Florent Wallet1Delphine Maucort-Boulch2Mathieu Page3Mahmoud Kaaki4Mathieu Schoeffler5Brenton Alexander6Olivier Desebbe7Service de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, FranceService de Réanimation, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, Pierre-Bénite, FranceHospices Civils de Lyon, Service de Biostatistique, Lyon, FranceDepartment of Anesthesiology and Critical Care Medicine, Pavilion P, Edouard Herriot Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, 69003 Lyon, FranceIntensive Care Unit, Centre Hospitalier de Roanne, 42300 Roanne, FranceUnité de Réanimation Chirurgicale, Hospices Civils de Lyon, Hôpital de la Croix-Rousse, Université de Lyon, 69004 Lyon, FranceDepartment of Anesthesiology & Perioperative Care, School of Medicine, University of California, Irvine, Orange, CA 92868, USADepartment of Anesthesiology and Intensive Care, Clinique de la Sauvegarde, 69009 Lyon, FrancePulse pressure variation can predict fluid responsiveness in strict applicability conditions. The purpose of this study was to describe the clinical applicability of pulse pressure variation during episodes of patient hemodynamic instability in the intensive care unit. We conducted a five-day, seven-center prospective study that included patients presenting with an unstable hemodynamic event. The six predefined inclusion criteria for pulse pressure variation applicability were as follows: mechanical ventilation, tidal volume >7 mL/kg, sinus rhythm, no spontaneous breath, heart rate/respiratory rate ratio >3.6, absence of right ventricular dysfunction, or severe valvulopathy. Seventy-three patients presented at least one unstable hemodynamic event, with a total of 163 unstable hemodynamic events. The six predefined criteria for the applicability of pulse pressure variation were completely present in only 7% of these. This data indicates that PPV should only be used alongside a strong understanding of the relevant physiology and applicability criteria. Although these exclusion criteria appear to be profound, they likely represent an absolute contraindication of use for only a minority of critical care patients.http://dx.doi.org/10.1155/2016/7162190 |
| spellingShingle | Bertrand Delannoy Florent Wallet Delphine Maucort-Boulch Mathieu Page Mahmoud Kaaki Mathieu Schoeffler Brenton Alexander Olivier Desebbe Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study Critical Care Research and Practice |
| title | Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study |
| title_full | Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study |
| title_fullStr | Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study |
| title_full_unstemmed | Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study |
| title_short | Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study |
| title_sort | applicability of pulse pressure variation during unstable hemodynamic events in the intensive care unit a five day prospective multicenter study |
| url | http://dx.doi.org/10.1155/2016/7162190 |
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