Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol

Introduction Blackwater fever (BWF), a complication of malaria, has in the past been considered as a rare complication of malaria in children living in high transmission settings. More recently, however, a growing number of paediatric clusters of BWF cases have been reported predominantly in sub-Sah...

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Main Authors: Julian Abeso, Francis Okello, Peter Olupot-Olupot, George Paasi, Carolyne Ndila, Florence Alaroker, Glorias Asiimwe
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/7/e059875.full
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author Julian Abeso
Francis Okello
Peter Olupot-Olupot
George Paasi
Carolyne Ndila
Florence Alaroker
Glorias Asiimwe
author_facet Julian Abeso
Francis Okello
Peter Olupot-Olupot
George Paasi
Carolyne Ndila
Florence Alaroker
Glorias Asiimwe
author_sort Julian Abeso
collection DOAJ
description Introduction Blackwater fever (BWF), a complication of malaria, has in the past been considered as a rare complication of malaria in children living in high transmission settings. More recently, however, a growing number of paediatric clusters of BWF cases have been reported predominantly in sub-Saharan Africa (SSA). The aim of this study is to map evidence on BWF among children in SSA from 1 January 1960 to 31 December 2021.Methods and analysis This review will be guided by Arksey and O’ Malley’s methodological framework for scoping reviews with methodological refinements by Levac et al and will comply with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews’ guidelines. Five electronic databases (MEDLINE via PubMed, Embase, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature (CINAHL) and PsycINFO) will be systematically searched using predefined keywords. In addition, reference lists of included articles will be searched. Our multidisciplinary team has formulated search strategies and two reviewers will independently complete study eligibility screening, final selection and data extraction. A third reviewer will adjudicate the final decision on disputed articles. Bibliographic data and abstract content will be collected and analysed using a data-charting tool developed iteratively by the research team.Ethics and dissemination This scoping review being a secondary analysis does not require ethics approval. We anticipate results of this review will broaden understanding of paediatric BWF in SSA and identify its research gaps in SSA. We will be disseminating results through journals and conferences targeting primary care providers.
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spelling doaj-art-094a7338122b4ea78e9a77b3de1a3d652025-01-30T19:50:08ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-059875Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocolJulian Abeso0Francis Okello1Peter Olupot-Olupot2George Paasi3Carolyne Ndila4Florence Alaroker5Glorias Asiimwe6Department of Paediatric and Child Health, Mbale Regional Referral Hospital, Mbale, UgandaDepartment of Public Health, Busitema University, Tororo, UgandaClinical trials department, Mbale Clinical Research Institute, Mbale, UgandaClinical trials unit at Mbale clinical research Institute, Mbale Clinical Research institute, Mbale, UgandaClinical trials department, Mbale Clinical Research Institute, Mbale, UgandaDepartment of Paediatric and Child Health, Soroti Regional Referral Hospital, Soroti, UgandaFaculty of Health Sciences university library, Busitema University, Tororo, UgandaIntroduction Blackwater fever (BWF), a complication of malaria, has in the past been considered as a rare complication of malaria in children living in high transmission settings. More recently, however, a growing number of paediatric clusters of BWF cases have been reported predominantly in sub-Saharan Africa (SSA). The aim of this study is to map evidence on BWF among children in SSA from 1 January 1960 to 31 December 2021.Methods and analysis This review will be guided by Arksey and O’ Malley’s methodological framework for scoping reviews with methodological refinements by Levac et al and will comply with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews’ guidelines. Five electronic databases (MEDLINE via PubMed, Embase, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature (CINAHL) and PsycINFO) will be systematically searched using predefined keywords. In addition, reference lists of included articles will be searched. Our multidisciplinary team has formulated search strategies and two reviewers will independently complete study eligibility screening, final selection and data extraction. A third reviewer will adjudicate the final decision on disputed articles. Bibliographic data and abstract content will be collected and analysed using a data-charting tool developed iteratively by the research team.Ethics and dissemination This scoping review being a secondary analysis does not require ethics approval. We anticipate results of this review will broaden understanding of paediatric BWF in SSA and identify its research gaps in SSA. We will be disseminating results through journals and conferences targeting primary care providers.https://bmjopen.bmj.com/content/12/7/e059875.full
spellingShingle Julian Abeso
Francis Okello
Peter Olupot-Olupot
George Paasi
Carolyne Ndila
Florence Alaroker
Glorias Asiimwe
Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol
BMJ Open
title Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol
title_full Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol
title_fullStr Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol
title_full_unstemmed Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol
title_short Resurgence of blackwater fever among children in sub-Saharan Africa: a scoping review protocol
title_sort resurgence of blackwater fever among children in sub saharan africa a scoping review protocol
url https://bmjopen.bmj.com/content/12/7/e059875.full
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