Rational engineering of DNA-nanoparticle motor with high speed and processivity comparable to motor proteins

Abstract DNA-nanoparticle motor is a burnt-bridge Brownian ratchet moving on RNA-modified surface driven by Ribonuclease H (RNase H), and one of the fastest nanoscale artificial motors. However, its speed is still much lower than those of motor proteins. Here we resolve elementary processes of motio...

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Bibliographic Details
Main Authors: Takanori Harashima, Akihiro Otomo, Ryota Iino
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56036-0
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