KETAMIR-2, a new molecular entity and novel ketamine analog

Ketamir-2 is a new molecular entity, and a novel ketamine analog designed to improve oral bioavailability, and offer a superior safety profile compared to existing ketamine treatments. It was found that Ketamir-2 is a low affinity NMDA receptor antagonist, that selectively binds to the PCP site. Its...

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Bibliographic Details
Main Authors: Itzchak Angel, Rita Perelroizen, Wendy Deffains, Florian W. Adraoui, Eddy Pichinuk, Erez Aminov
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1606976/full
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