Model-Based Analysis of Flow-Mediated Dilation and Intima-Media Thickness
We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function. The video sequences are acquired from a B-mode echographic scanner. A spline model (deformable template) is fitted to the data t...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2008-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2008/738545 |
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| Summary: | We present an end-to-end system for the automatic measurement of flow-mediated dilation (FMD) and intima-media thickness (IMT) for the assessment of the arterial function.
The video sequences are acquired from a B-mode echographic
scanner. A spline model (deformable template) is fitted to the
data to detect the artery boundaries and track them all along
the video sequence. The a priori knowledge about the image
features and its content is exploited. Preprocessing is performed
to improve both the visual quality of video frames for visual
inspection and the performance of the segmentation algorithm
without affecting the accuracy of the measurements. The system
allows real-time processing as well as a high level of interactivity
with the user. This is obtained by a graphical user interface
(GUI) enabling the cardiologist to supervise the whole process
and to eventually reset the contour extraction at any point in time.
The system was validated and the accuracy, reproducibility, and
repeatability of the measurements were assessed with extensive
in vivo experiments. Jointly with the user friendliness, low cost,
and robustness, this makes the system suitable for both research
and daily clinical use. |
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| ISSN: | 1687-4188 1687-4196 |