New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine

The occurrence of a new strain of SARS-CoV-2 cannot be ruled out. Therefore, this study seeks to investigate the possible effects of a hypothetical imperfect anti-COVID-19 vaccine on the control of not only the first variant of SARS-CoV-2 but also the second (new) variant of SARS-CoV-2. We further e...

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Main Authors: Taye Samuel Faniran, Aatif Ali, Nawal E. Al-Hazmi, Joshua Kiddy K. Asamoah, Taher A. Nofal, Matthew O. Adewole
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2022/1062180
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author Taye Samuel Faniran
Aatif Ali
Nawal E. Al-Hazmi
Joshua Kiddy K. Asamoah
Taher A. Nofal
Matthew O. Adewole
author_facet Taye Samuel Faniran
Aatif Ali
Nawal E. Al-Hazmi
Joshua Kiddy K. Asamoah
Taher A. Nofal
Matthew O. Adewole
author_sort Taye Samuel Faniran
collection DOAJ
description The occurrence of a new strain of SARS-CoV-2 cannot be ruled out. Therefore, this study seeks to investigate the possible effects of a hypothetical imperfect anti-COVID-19 vaccine on the control of not only the first variant of SARS-CoV-2 but also the second (new) variant of SARS-CoV-2. We further examine the rates r and a, escape of quarantined infectious individuals from isolation centers. The control Rc and basic reproduction numbers R0 are computed which gives assess to obtain asymptotic stability of disease-free equilibrium point globally and the existence of a unique persistent equilibrium solution. Numerical results reveal that people infected with the second strain who are vaccinated with an imperfect vaccine are under control but the prevalence of the second variant enhances the prevalence of the first variant. Thus, discovering a vaccine that is effective (to a good extent) for the prevention of variant 2 (new variant) is necessary for the control of COVID-19. Numerical results also reveal that increase in the rate at which individuals infected with the first variant escape the isolation center gives rise to the population infected with the first variant and lowers the peak of the population infected with the second variant. This is probably because individuals infected with the second variant appear to be more careful with their lives and get vaccinated more than individuals infected with the first variant.
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spelling doaj-art-084ffc27b5bb46f6a14b35ae20ee124f2025-02-03T06:04:44ZengWileyComplexity1099-05262022-01-01202210.1155/2022/1062180New Variant of SARS-CoV-2 Dynamics with Imperfect VaccineTaye Samuel Faniran0Aatif Ali1Nawal E. Al-Hazmi2Joshua Kiddy K. Asamoah3Taher A. Nofal4Matthew O. Adewole5Department of Computer ScienceDepartment of MathematicsDepartment of ChemistryDepartment of MathematicsDepartment of Mathematics and StatisticsDepartment of Computer Science and MathematicsThe occurrence of a new strain of SARS-CoV-2 cannot be ruled out. Therefore, this study seeks to investigate the possible effects of a hypothetical imperfect anti-COVID-19 vaccine on the control of not only the first variant of SARS-CoV-2 but also the second (new) variant of SARS-CoV-2. We further examine the rates r and a, escape of quarantined infectious individuals from isolation centers. The control Rc and basic reproduction numbers R0 are computed which gives assess to obtain asymptotic stability of disease-free equilibrium point globally and the existence of a unique persistent equilibrium solution. Numerical results reveal that people infected with the second strain who are vaccinated with an imperfect vaccine are under control but the prevalence of the second variant enhances the prevalence of the first variant. Thus, discovering a vaccine that is effective (to a good extent) for the prevention of variant 2 (new variant) is necessary for the control of COVID-19. Numerical results also reveal that increase in the rate at which individuals infected with the first variant escape the isolation center gives rise to the population infected with the first variant and lowers the peak of the population infected with the second variant. This is probably because individuals infected with the second variant appear to be more careful with their lives and get vaccinated more than individuals infected with the first variant.http://dx.doi.org/10.1155/2022/1062180
spellingShingle Taye Samuel Faniran
Aatif Ali
Nawal E. Al-Hazmi
Joshua Kiddy K. Asamoah
Taher A. Nofal
Matthew O. Adewole
New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine
Complexity
title New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine
title_full New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine
title_fullStr New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine
title_full_unstemmed New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine
title_short New Variant of SARS-CoV-2 Dynamics with Imperfect Vaccine
title_sort new variant of sars cov 2 dynamics with imperfect vaccine
url http://dx.doi.org/10.1155/2022/1062180
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