Probing the release of the chronobiotic hormone melatonin from hybrid calcium alginate hydrogel beads

Probing the release of the chronobiotic hormone melatonin from hybrid calcium alginate hydrogel beads

A variety of commonly used hydrogels were utilized in the preparation of calcium alginate beads, which incorporate the chronobiotic hormone melatonin (MLT). The in vitro release of the hormone in aqueous media at pH 1.2 and 6.8 was probed in the conjunction with the swelling of the beads and their t...

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Bibliographic Details
Main Authors: Vlachou Marilena, Siamidi Angeliki, Goula Efstratia, Georgas Panagiotis, Pippa Natassa, Karalis Vangelis, Sentoukas Theodore, Pispas Stergios
Format: Article
Language:English
Published: Sciendo 2020-12-01
Series:Acta Pharmaceutica
Subjects:
melatonin
hydrogels
calcium alginate beads
swelling behavior
thermogravimetric analysis
in vitro release
Online Access:https://doi.org/10.2478/acph-2020-0037
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https://doi.org/10.2478/acph-2020-0037

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